Alameda, CA November 20, 2023 – Magnetic Insight, a leader in Magnetic Particle Imaging (MPI) is pleased to announce the funding of a Small Business Innovation Research (SBIR) grant titled “Development of a prototype clinical theranostic platform combining Magnetic Particle Imaging (MPI) and Magnetic Fluid Hyperthermia (MFH) for the treatment of brain tumors.”
This groundbreaking project represents a significant step forward in the field of cancer treatment, with a specific focus on addressing the challenges associated with imaging and treating brain tumors.
The objective of this SBIR grant proposal is to develop an integrated, human brain-sized clinical theranostic platform that combines MPI and Magnetic Fluid Hyperthermia (MFH). This revolutionary platform will provide an innovative approach to treating brain tumors, offering a combination of localized heating and tomographic temperature monitoring during treatment.
MFH is a promising technology that relies on the delivery of magnetic nanoparticles to tumors followed by the application of alternating magnetic fields. This results in localized heating of the tumor tissue, leading to the killing of cancer cells. MFH can be used in conjunction with radiotherapy or chemotherapy to enhance their cytotoxic effects.
“Magnetic Insight is excited to be at the forefront of this transformative research, working to improve the treatment options for brain tumor patients and potentially revolutionizing the field of cancer therapy,” says Patrick Goodwill, CTO and CEO of Magnetic Insight. “The successful development of this theranostic platform has the potential to significantly impact the lives of patients worldwide.”
This collaborative project will be headed by Johns Hopkins professor Dr. Robert Ivkov. Dr. Ivkov, Professor of Radiation Oncology and Molecular Radiation Sciences and Oncology at the Johns Hopkins University School of Medicine, is the principal investigator for the project. His research interests include the development, characterization, and use of nanomaterials to target cancer and to enhance the effectiveness of current therapies such as radiation. He has a particular focus on selective heating with magnetic nanoparticles.
The research reported in this press release is supported by the National Cancer Institute of the National Institutes of Health (NIH) under project number 1R44CA285064-01.
The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health or Johns Hopkins University.